Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.43 |
| ▸ | FNTB | P49356 | 5/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569644 | 0.90 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL7563110 | 0.88 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| SCHEMBL7561794 | 0.83 | FNTA (0.40) | FNTAFNTBPGGT1BCYP19A1CYP3A4 | |
| SCHEMBL7562658 | 0.83 | FNTA (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL8211342 | 0.82 | FNTA (0.42) | FNTAFNTBPGGT1BCYP3A4CYP2D6 | |
| SCHEMBL7564790 | 0.82 | FNTA (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL7571016 | 0.81 | CYP19A1 (0.46) | FNTAFNTBPGGT1BCYP19A1PTGS2 | |
| SCHEMBL7563915 | 0.81 | FNTA (0.51) | FNTAFNTBPGGT1BCYP19A1CYP3A4 | |
| SCHEMBL7668399 | 0.79 | FNTA (0.45) | FNTAFNTB | |
| SCHEMBL7668406 | 0.79 | FNTA (0.45) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | claimed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | claimed |