Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 5/20 | 1.00 |
| ▸ | VDR | P11473 | 16/20 | 0.95 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014789 | 1.00 | HDAC6 (1.00) | HDAC6HDAC3VDRHDAC2 | |
| SCHEMBL8006551 | 0.97 | VDR (1.00) | HDAC6HDAC3VDRHDAC2 | |
| SCHEMBL8226141 | 0.97 | VDR (1.00) | HDAC6HDAC3VDRHDAC2 | |
| SCHEMBL13532024 | 0.90 | HDAC6 (0.81) | HDAC6HDAC3VDRHDAC2 | |
| SCHEMBL13531885 | 0.90 | HDAC6 (0.81) | HDAC6HDAC3VDRHDAC2 | |
| SCHEMBL3185156 | 0.89 | HDAC6 (0.81) | HDAC6HDAC3VDRHDAC2 | |
| SCHEMBL8008890 | 0.88 | VDR (0.82) | HDAC6HDAC3VDRHDAC2 | |
| SCHEMBL7997232 | 0.88 | HDAC6 (0.78) | HDAC6HDAC3VDRHDAC2 | |
| SCHEMBL13531887 | 0.87 | VDR (0.82) | HDAC6HDAC3VDRHDAC2 | |
| SCHEMBL7999288 | 0.87 | VDR (0.80) | HDAC6HDAC3VDRHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007131364-A1 | HYBRID MOLECULES HAVING MIXED VITAMIN D RECEPTOR AGONISM AND HISTONE DEACETYLASE INHIBITORY PROPERTIES | MCGILL UNIVERSITY (CA) | 2007-11-22 | — | — | WO | disclosed |