SCHEMBL8225166 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	14/20	0.58

▸	ACKR3	P25106	2/20	0.39

▸	HDAC1	Q13547	2/20	0.34

▸	HDAC3	O15379	1/20	0.34

▸	HDAC4	P56524	1/20	0.34

▸	HDAC7	Q8WUI4	1/20	0.34

▸	HDAC2	Q92769	1/20	0.34

▸	F2	P00734	1/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	FPR1	P21462	1/20	0.32

▸	FPR2	P25090	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3979465	0.91	F10 (0.60)	F10ACKR3HDAC1HDAC3HDAC4
SCHEMBL8233573	0.90	F10 (0.59)	F10ACKR3HDAC1HDAC3HDAC4
SCHEMBL8230409	0.88	F10 (0.44)	F10ACKR3HDAC1
SCHEMBL8230162	0.88	F10 (0.56)	F10ACKR3HDAC1ALDH1A1HPGD
SCHEMBL8226339	0.86	F10 (0.62)	F10ACKR3HDAC1HDAC3HDAC4
SCHEMBL8231708	0.84	F10 (0.59)	F10ACKR3HDAC1HDAC3HDAC4
SCHEMBL8230158	0.84	F10 (0.61)	F10ACKR3HDAC1HDAC3HDAC4
SCHEMBL8230046	0.83	F10 (0.61)	F10ACKR3HDAC1HDAC3HDAC4
SCHEMBL8230048	0.83	F10 (0.52)	F10ACKR3HDAC1HDAC3HDAC4
SCHEMBL8225992	0.82	F10 (0.61)	F10ACKR3HDAC1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007137790-A1	ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF	BAYER HEALTHCARE AG (DE)	2007-12-06	—	—	WO	disclosed