Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 5/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915359 | 0.91 | F10 (0.46) | F10ACKR3PREPPARP1NR1I2 | |
| SCHEMBL8225166 | 0.88 | F10 (0.58) | F10ACKR3HDAC1 | |
| SCHEMBL8234420 | 0.88 | F10 (0.43) | F10ACKR3PREPPARP1NR1I2 | |
| SCHEMBL8230000 | 0.86 | F10 (0.47) | F10ACKR3PREPPARP1HDAC1 | |
| SCHEMBL8230631 | 0.84 | F10 (0.45) | F10ACKR3PREPPARP1HDAC1 | |
| SCHEMBL8230871 | 0.84 | F10 (0.46) | F10ACKR3PREPPARP1NR1I2 | |
| SCHEMBL3987546 | 0.84 | F10 (0.42) | F10ACKR3PREPNR1I2UGCG | |
| SCHEMBL8230012 | 0.82 | F10 (0.46) | F10ACKR3PREPPARP1NR1I2 | |
| SCHEMBL8230473 | 0.82 | F10 (0.47) | F10ACKR3PREPPARP1HDAC1 | |
| SCHEMBL8230535 | 0.81 | F10 (0.52) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137790-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |