Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20081607 | 0.82 | CDK5 (0.42) | CLK1CDK5CDK5R1GSK3BDYRK1A | |
| SCHEMBL823112 | 0.82 | CLK1 (0.45) | CLK1CDK5CDK5R1GSK3BDYRK1A | |
| SCHEMBL20081605 | 0.79 | CLK1 (0.39) | CLK1CDK5CDK5R1GSK3BDYRK1A | |
| SCHEMBL14406351 | 0.76 | SSTR2 (0.57) | CLK1CDK5CDK5R1GSK3BDYRK1A | |
| SCHEMBL3618586 | 0.73 | CLK1 (0.52) | CLK1CDK5CDK5R1GSK3BDYRK1A | |
| SCHEMBL20017671 | 0.72 | CLK1 (0.58) | CLK1CDK5CDK5R1GSK3BDYRK1A | |
| SCHEMBL27361882 | 0.71 | CLK1 (0.59) | CLK1CDK5CDK5R1GSK3BDYRK1A | |
| SCHEMBL25034156 | 0.69 | MAPT (0.57) | CLK1CDK5CDK5R1GSK3BDYRK1A | |
| SCHEMBL3435669 | 0.68 | CYP2A6 (0.55) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12425727 | 0.68 | CYP2A6 (0.55) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940020-B1 | LUCIFERIN LUMINESCENT SUBSTRATE OF MARINE OSTRACOD CRUSTACEAN AND METHOD FOR PRODUCTION THEREOF | AIST (JP) | 2018-04-25 | — | — | EP | disclosed |
| EP-2940020-A1 | LUCIFERIN LUMINESCENT SUBSTRATE OF MARINE OSTRACOD CRUSTACEAN AND METHOD FOR PRODUCTION THEREOF | National Institute of Advanced Industrial Science and Technology (JP) | 2015-11-04 | — | — | EP | disclosed |
| EP-1930332-B1 | LUMINESCENT VARGULA LUCIFERIN SUBSTRATE AND PROCESS FOR PRODUCING THE SAME | NAT INST OF ADVANCED IND SCIEN (JP) | 2015-06-03 | — | — | EP | disclosed |
| US-8343729-B2 | Luciferin luminescent substrate of marine ostracod crustacean and method for production thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2013-01-01 | — | — | US | disclosed |
| US-8343729-B2 | Luciferin luminescent substrate of marine ostracod crustacean and method for production thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20110287459-A1 | Luciferin luminescent substrate of marine ostracod crustacean and method for production thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110287459-A1 | Luciferin luminescent substrate of marine ostracod crustacean and method for production thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-11-24 | — | — | US | disclosed |
| US-7989621-B2 | Method for producing substituted imidazo[1,2-A]pyrazines of (s)-1-(3-(2-sec-butyl-6-(1h-indol-3-yl)-3-oxo-3,7-dihydroimadazo[1,2-a]pyrazin-8-yl)propyl)guanidine | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-08-02 | — | — | US | disclosed |
| US-7989621-B2 | Method for producing substituted imidazo[1,2-A]pyrazines of (s)-1-(3-(2-sec-butyl-6-(1h-indol-3-yl)-3-oxo-3,7-dihydroimadazo[1,2-a]pyrazin-8-yl)propyl)guanidine | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-08-02 | — | — | US | disclosed |
| US-20090136974-A1 | Luciferin Luminescent Substrate of Marine Ostracod Crustacean and Method for Production Thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE TECHNOLOGY (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20090136974-A1 | Luciferin Luminescent Substrate of Marine Ostracod Crustacean and Method for Production Thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE TECHNOLOGY (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1930332-A1 | LUMINESCENT VARGULA LUCIFERIN SUBSTRATE AND PROCESS FOR PRODUCING THE SAME | National Institute Of Advanced Industrial Science and Technology (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136974-A1 | Luciferin Luminescent Substrate of Marine Ostracod Crustacean and Method for Production Thereof | GLB1, DCXR, GALR1 | CLK1 1939/4885CDK5 4285/4885CDK5R1 3478/4885 |
| US-20110287459-A1 | Luciferin luminescent substrate of marine ostracod crustacean and method for production thereof | GLB1, DCXR, GALR1 | CLK1 1939/4885CDK5 4285/4885CDK5R1 3478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.