SCHEMBL8225837

SCHEMBL8225837

CCCC[C@@]1(CC)CS(=O)(=O)c2cc(OCC)ccc2C(c2ccccc2)N1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2486216 1.00 SLC10A2 (0.72) SLC10A2
SCHEMBL2486212 1.00 SLC10A2 (0.72) SLC10A2
SCHEMBL8225832 1.00 SLC10A2 (0.72) SLC10A2
SCHEMBL2457392 0.91 SLC10A2 (0.77) SLC10A2
SCHEMBL9961456 0.91 SLC10A2 (0.77) SLC10A2
SCHEMBL2457393 0.91 SLC10A2 (0.77) SLC10A2
SCHEMBL22285894 0.91 SLC10A2 (0.77) SLC10A2
SCHEMBL1361642 0.91 SLC10A2 (0.74) SLC10A2
SCHEMBL2946578 0.91 SLC10A2 (0.74) SLC10A2
SCHEMBL1361639 0.91 SLC10A2 (0.74) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0971744-A2 COMBINATION THERAPY EMPLOYING ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS G.D. SEARLE & CO. (US) 2000-01-19 EP disclosed
WO-1998040375-A2 COMBINATION OF ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS G.D. SEARLE & CO. (US) 1998-09-17 WO disclosed