Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8225849

CCCCCN1CCCC1C(=O)O.N

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.49
S1PR1 P21453 3/20 0.48
S1PR3 Q99500 3/20 0.48
S1PR5 Q9H228 3/20 0.48
S1PR4 O95977 1/20 0.48
OPRD1 P41143 1/20 0.45
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
KCNH2 Q12809 1/20 0.44
POLB P06746 1/20 0.44
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
BCHE P06276 7/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GBA1 P04062 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1381895 0.98 NR1I2 (0.50) NR1I2S1PR1S1PR3S1PR5S1PR4
SCHEMBL1381896 0.98 NR1I2 (0.50) NR1I2S1PR1S1PR3S1PR5S1PR4
SCHEMBL8674297 0.97 S1PR1 (0.51) NR1I2S1PR1S1PR3S1PR5S1PR4
SCHEMBL9150667 0.97 S1PR1 (0.51) NR1I2S1PR1S1PR3S1PR5S1PR4
SCHEMBL28637428 0.97 S1PR1 (0.51) NR1I2S1PR1S1PR3S1PR5S1PR4
SCHEMBL20442187 0.97 S1PR1 (0.51) NR1I2S1PR1S1PR3S1PR5S1PR4
SCHEMBL7263459 0.97 S1PR1 (0.51) NR1I2S1PR1S1PR3S1PR5S1PR4
SCHEMBL9150671 0.97 S1PR1 (0.51) NR1I2S1PR1S1PR3S1PR5S1PR4
SCHEMBL5513172 0.97 S1PR1 (0.51) NR1I2S1PR1S1PR3S1PR5S1PR4
SCHEMBL8674295 0.97 S1PR1 (0.51) NR1I2S1PR1S1PR3S1PR5S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108853339-A A kind of Chinese medicine composition for treating diabetes 东莞市东卓中天生物科技有限公司 2018-11-23 CN disclosed
CN-105585601-B Anti-aging skin external composition and preparation method thereof 株式会社林原 2018-11-13 CN disclosed
CN-108125229-A Maintenance heart and prevention myocardial infarction lead to the food of sudden death 东莞市东卓中天生物科技有限公司 2018-06-08 CN disclosed
CN-104918603-A Anti-aging skin external composition and preparation method thereof HAYASHIBARA CO 2015-09-16 CN disclosed
WO-2000014219-A9 PEPTIDE NUCLEIC ACID-OLIGOADENYLATE CHIMERIC MOLECULES US GOV HEALTH & HUMAN SERV (US) 2000-08-10 WO disclosed
WO-2000014219-A2 PEPTIDE NUCLEIC ACID-OLIGOADENYLATE CHIMERIC MOLECULES THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2000-03-16 WO disclosed