Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381896 | 1.00 | NR1I2 (0.50) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL7263459 | 0.98 | S1PR1 (0.51) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL9150667 | 0.98 | S1PR1 (0.51) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL28637428 | 0.98 | S1PR1 (0.51) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL20442187 | 0.98 | S1PR1 (0.51) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| Ammonia Solution, Strong SCHEMBL8225849 | 0.98 | NR1I2 (0.49) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL8674297 | 0.98 | S1PR1 (0.51) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL9150671 | 0.98 | S1PR1 (0.51) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL5513172 | 0.98 | S1PR1 (0.51) | NR1I2S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL8674295 | 0.98 | S1PR1 (0.51) | NR1I2S1PR1S1PR3S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104583228-B | acyl dipeptide derivatives | 味之素株式会社 | 2018-09-28 | — | — | CN | claimed |
| EP-2889306-B1 | ACYL DIPEPTIDE DERIVATIVE | AJINOMOTO KK (JP) | 2018-09-19 | — | — | EP | claimed |
| CN-104661643-B | Humectant and cosmetic containing the same | 味之素株式会社 | 2018-04-20 | — | — | CN | claimed |
| EP-2832345-B1 | COSMETIC COMPOSITION | AJINOMOTO KK (JP) | 2017-11-22 | — | — | EP | claimed |
| CN-107349125-A | NMF and the cosmetics containing NMF | 味之素株式会社 | 2017-11-17 | — | — | CN | claimed |
| CN-106455664-A | Composition with high content of cyclic dipeptide | 三得利控股株式会社 | 2017-02-22 | — | — | CN | claimed |
| CN-106456633-A | Sugar metabolism improving agent | 三得利控股株式会社 | 2017-02-22 | — | — | CN | claimed |
| CN-106214504-A | Cosmetic combination | 味之素株式会社 | 2016-12-14 | — | — | CN | claimed |
| US-9464110-B2 | Acyl dipeptide derivative | AJINOMOTO CO., INC. (JP) | 2016-10-11 | — | — | US | claimed |
| CN-104244919-B | Cosmetic composition | 味之素株式会社 | 2016-06-29 | — | — | CN | claimed |
| US-20050215573-A1 | Novel inhibitors of glutaminyl cyclase | PROBIODRUG AG | 2005-09-29 | — | — | US | claimed |
| WO-2005075436-A2 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2005-08-18 | — | — | WO | claimed |
| US-20050171112-A1 | Combinations useful for the treatment of neuronal disorders | PROBIODRUG AG | 2005-08-04 | — | — | US | claimed |
| WO-2005049027-A2 | COMBINATIONS USEFUL FOR THE TREATMENT OF NEURONAL DISORDERS | PROBIODRUG AG (DE) | 2005-06-02 | — | — | WO | claimed |
| WO-2005012320-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIMICROBIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2005-02-10 | — | — | WO | claimed |
| WO-2004098591-A2 | INHIBITORS OF GLUTAMINYL CYCLASE AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | PROBIODRUG AG (DE) | 2004-11-18 | — | — | WO | claimed |
| US-20040224875-A1 | Inhibitors of glutaminyl cyclase | PROBIODRUG AG (DE) | 2004-11-11 | — | — | US | claimed |
| WO-2003070243-A1 | DI-ESTER DERIVATIVES AS SHORT ACTING NEUROMUSCULAR BLOCKERS | THERASCI LIMITED (GB) | 2003-08-28 | — | — | WO | claimed |
| EP-0275522-B1 | Optically active 1-acyl-proline esters and their use as doping agents in liquid-crystal compositions | HOECHST AG (DE) | 1995-03-29 | — | — | EP | claimed |
| US-4915868-A | Display element | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171112-A1 | Combinations useful for the treatment of neuronal disorders | MME, DNPEP, DPP4 | NR1I2 2443/4885S1PR1 3450/4885S1PR3 2713/4885 |
| US-20040224875-A1 | Inhibitors of glutaminyl cyclase | GLS2, GLS, GLUL | NR1I2 2474/4885S1PR1 4194/4885S1PR3 4577/4885 |
| US-20050215573-A1 | Novel inhibitors of glutaminyl cyclase | GLS2, GLS, GLUL | NR1I2 3225/4885S1PR1 3930/4885S1PR3 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.