Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ATF4 | P18848 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 9/20 | 0.40 |
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | CDK14 | O94921 | 1/20 | 0.38 |
| ▸ | CCNY | Q8ND76 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286716 | 0.86 | CNR1 (0.54) | KDM4EALDH1A1SMN1; SMN2CNR1CNR2 | |
| SCHEMBL8221125 | 0.85 | DYRK1A (0.39) | EPHX2SMN1; SMN2TSHRJAK1MEN1 | |
| SCHEMBL8260921 | 0.82 | ACKR3 (0.45) | KDM4ECDK14CCNYMEN1KMT2A | |
| SCHEMBL8261197 | 0.79 | CDK5 (0.46) | CDK14CCNY | |
| SCHEMBL8261368 | 0.77 | HDAC4 (0.51) | ALDH1A1CNR1CNR2TSHRMEN1 | |
| SCHEMBL8219219 | 0.77 | CCR8 (0.57) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL24758664 | 0.76 | EPHX2 (0.54) | EPHX2CDK14CCNY | |
| SCHEMBL1286696 | 0.76 | HTR1A (0.46) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL8262988 | 0.75 | CDK14 (0.49) | EPHX2CDK14CCNY | |
| SCHEMBL29199176 | 0.74 | CDK14 (0.49) | EPHX2CDK14CCNY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009954-A1 | MEDICAL USE OF CYCLIN DEPENDENT KINASES INHIBITORS | ASTEX THERAPEUTICS LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |