Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14959465 | 0.85 | NAMPT (0.48) | NAMPT | |
| SCHEMBL8225764 | 0.82 | NAMPT (0.47) | NAMPTHDAC1HDAC8 | |
| SCHEMBL8212663 | 0.82 | NAMPT (0.48) | NAMPTHDAC8 | |
| SCHEMBL12187764 | 0.81 | POLB (0.46) | NAMPTDPP8DPP9DPP7 | |
| SCHEMBL11929934 | 0.80 | HDAC1 (0.54) | NAMPTHDAC1 | |
| SCHEMBL25091083 | 0.79 | NAMPT (0.54) | NAMPTHDAC8 | |
| SCHEMBL20873124 | 0.76 | LMNA (0.52) | NAMPT | |
| SCHEMBL20873101 | 0.74 | NAMPT (0.47) | NAMPTHDAC1 | |
| SCHEMBL20873104 | 0.74 | NAMPT (0.47) | NAMPTHDAC1 | |
| SCHEMBL20873114 | 0.74 | SMN1; SMN2 (0.50) | NAMPTHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133865-A2 | HCV/HIV INHIBITORS AN THEIR USES | NOVARTIS AG (CH) | 2007-11-22 | — | — | WO | disclosed |