Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31562964 | 0.81 | GRIA1 (0.47) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL8216824 | 0.80 | TUBB4A (0.47) | MAOBARCYP19A1GRIA1MAPT | |
| SCHEMBL31563001 | 0.78 | GRIA1 (0.58) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL31562979 | 0.76 | PARP1 (0.43) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL5618588 | 0.75 | HTR2C (0.55) | HTR2CHTR2BHTR2A | |
| SCHEMBL5619702 | 0.75 | HTR2C (0.55) | HTR2CHTR2BHTR2A | |
| SCHEMBL5618115 | 0.75 | HTR2C (0.55) | HTR2CHTR2BHTR2A | |
| SCHEMBL7377181 | 0.69 | — | — | |
| SCHEMBL31562965 | 0.68 | HSD17B10 (0.38) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL31562958 | 0.67 | AR (0.36) | MAOBADORA3ARKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006576-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2000-02-10 | — | — | WO | disclosed |