Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 17/20 | 0.77 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8227364 | 0.91 | THRB (0.75) | THRBRXFP1HDAC1 | |
| SCHEMBL8229324 | 0.91 | THRB (0.77) | THRBRXFP1 | |
| SCHEMBL5368006 | 0.87 | THRB (1.00) | THRBRXFP1HDAC1 | |
| SCHEMBL8228589 | 0.85 | THRB (0.75) | THRBRXFP1HDAC1 | |
| SCHEMBL8225984 | 0.81 | THRB (0.69) | THRBRXFP1HDAC1 | |
| SCHEMBL8229534 | 0.80 | THRB (0.68) | THRBRXFP1HDAC1 | |
| SCHEMBL8219823 | 0.78 | THRB (0.63) | THRBHDAC1 | |
| SCHEMBL8228464 | 0.78 | THRB (0.71) | THRBHDAC1 | |
| SCHEMBL8220856 | 0.78 | THRB (0.62) | THRBHDAC1 | |
| SCHEMBL8220860 | 0.77 | THRB (0.59) | THRBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |