Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099714 | 0.92 | TSHR (0.53) | TSHRDPP7L3MBTL1KMT2ACD274 | |
| SCHEMBL14068417 | 0.89 | CD274 (0.59) | TSHRDPP7L3MBTL1KMT2ACD274 | |
| SCHEMBL5096370 | 0.88 | TSHR (0.49) | TSHRDPP7L3MBTL1KMT2ACD274 | |
| SCHEMBL5105109 | 0.88 | MEN1 (0.67) | TSHRDPP7KMT2ACD274MEN1 | |
| SCHEMBL5105365 | 0.86 | CD274 (0.57) | TSHRKMT2ACD274MEN1 | |
| SCHEMBL9461580 | 0.84 | L3MBTL1 (0.55) | TSHRDPP7L3MBTL1KMT2ACD274 | |
| SCHEMBL5099100 | 0.83 | CD274 (0.65) | TSHRKMT2ACD274MEN1 | |
| SCHEMBL5105141 | 0.83 | CD274 (0.54) | TSHRKMT2ACD274MEN1 | |
| SCHEMBL5096216 | 0.81 | DPP7 (0.53) | TSHRDPP7L3MBTL1KMT2ACD274 | |
| SCHEMBL5105512 | 0.80 | MEN1 (0.77) | DPP7KMT2ACD274MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |