Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 8/20 | 0.78 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | CASP4 | P49662 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | CASP9 | P55211 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867072 | 0.94 | SNCA (0.70) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL29214118 | 0.94 | SNCA (0.70) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL30777324 | 0.92 | SNCA (0.71) | SNCAL3MBTL1NR1H2NR1H3TDP1 | |
| SCHEMBL11725544 | 0.92 | SNCA (0.71) | SNCAL3MBTL1NR1H2NR1H3TDP1 | |
| SCHEMBL28738324 | 0.91 | SNCA (0.67) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL29151192 | 0.88 | SNCA (0.64) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL29151195 | 0.85 | SNCA (0.60) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL17356869 | 0.81 | SNCA (0.56) | SNCACASP1CASP3CASP4CASP7 | |
| SCHEMBL1208152 | 0.80 | SNCA (0.86) | SNCASIRT2NOX1GAAMAPT | |
| SCHEMBL29850622 | 0.80 | SNCA (0.86) | SNCASIRT2NOX1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457905-A1 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | Wista Laboratories Ltd. (SG) | 2012-05-30 | — | — | EP | disclosed |
| EP-2457904-A1 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | Wista Laboratories Ltd. (SG) | 2012-05-30 | — | — | EP | disclosed |
| WO-2008007074-A2 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2008-01-17 | — | — | WO | disclosed |