Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 8/20 | 0.86 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29850622 | 1.00 | SNCA (0.86) | SNCANOX1MAPK1MAPTLMNA | |
| SCHEMBL21752000 | 0.93 | SNCA (1.00) | SNCANOX1MAPK1MAPTLMNA | |
| SCHEMBL19398391 | 0.93 | SNCA (0.76) | SNCANOX1MAPK1MAPTLMNA | |
| SCHEMBL17591100 | 0.89 | SNCA (0.71) | SNCANOX1MAPK1MAPTLMNA | |
| SCHEMBL21751995 | 0.89 | SNCA (1.00) | SNCANOX1MAPK1MAPTLMNA | |
| SCHEMBL21771119 | 0.82 | SNCA (0.71) | SNCAMAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8226386 | 0.80 | SNCA (0.78) | SNCANOX1MAPTGAASIRT2 | |
| SCHEMBL17999732 | 0.79 | SNCA (0.84) | SNCAMAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17999733 | 0.79 | SNCA (0.84) | SNCAMAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18408660 | 0.79 | SNCA (0.58) | SNCAMAPK1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382220-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2016-07-05 | — | — | US | claimed |
| US-20130317012-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2013-11-28 | — | — | US | claimed |
| EP-2057136-B1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LAB LTD (SG) | 2013-05-22 | — | — | EP | claimed |
| US-20110294795-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. | 2011-12-01 | — | — | US | claimed |
| US-7956183-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2011-06-07 | — | — | US | claimed |
| EP-2057136-A2 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | Wista Laboratories Ltd. (SG) | 2009-05-13 | — | — | EP | claimed |
| WO-2008007074-A2 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2008-01-17 | — | — | WO | claimed |
| US-20250325557-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2025-10-23 | — | — | US | disclosed |
| US-20250222006-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2025-07-10 | — | — | US | disclosed |
| US-12324810-B2 | 3, 7-diamino-10H-phenothiazine salts and their use | WISTA LABORATORIES LTD. (SG) | 2025-06-10 | — | — | US | disclosed |
| US-12215234-B2 | Process for the purification of methylene blue | RK Pharma Solutions LLC (US) | 2025-02-04 | — | — | US | disclosed |
| US-20250000871-A1 | PHENOTHIAZINE DIAMINIUM SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2025-01-02 | — | — | US | disclosed |
| US-12064439-B2 | Phenothiazine diaminium salts and their use | WISTA LABORATORIES LTD. (SG) | 2024-08-20 | — | — | US | disclosed |
| EP-2013191-A2 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | Wista Laboratories Ltd. (SG) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008007074-A2 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008007074-A2 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2008-01-17 | — | — | WO | disclosed |
| WO-2007110627-A2 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007110627-A2 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2007-10-04 | — | — | WO | disclosed |
| US-20070129543-A1 | PROCESSES FOR PREPARING NOVEL METHYLENE BLUE DERIVATIVE | VERFICATION TECHNOLOGIES, INC. (US) | 2007-06-07 | — | — | US | disclosed |
| US-7176308-B2 | Processes for preparing novel methylene blue derivative | VERIFICATION TECHNOLOGIES, INC. (US) | 2007-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325557-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | PSEN1, PSEN2, APP | SNCA 673/4885NOX1 187/4885MAPK1 2122/4885 |
| US-12324810-B2 | 3, 7-diamino-10H-phenothiazine salts and their use | PSEN1, PSEN2, APP | SNCA 467/4885NOX1 347/4885MAPK1 2626/4885 |
| US-12064439-B2 | Phenothiazine diaminium salts and their use | QDPR, SLC35A1, SLC6A7 | SNCA 427/4885NOX1 2683/4885MAPK1 2095/4885 |
| US-20250222006-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MB, TPMT, HBB | SNCA 173/4885NOX1 1655/4885MAPK1 3258/4885 |
| US-20070129543-A1 | PROCESSES FOR PREPARING NOVEL METHYLENE BLUE DERIVATIVE | MB, HMBS, KIT | SNCA 266/4885NOX1 3596/4885MAPK1 4219/4885 |
| US-20130317012-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MAPT, TPMT, UROD | SNCA 227/4885NOX1 4259/4885MAPK1 2664/4885 |
| US-20110294795-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MMAB, MB, ABCB7 | SNCA 1425/4885NOX1 3149/4885MAPK1 2386/4885 |
| US-20250000871-A1 | PHENOTHIAZINE DIAMINIUM SALTS AND THEIR USE | QDPR, SLC35A1, SLC6A7 | SNCA 427/4885NOX1 2683/4885MAPK1 2095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.