Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8257019 | 0.85 | NPSR1 (0.43) | NPSR1MAPTDAOCTPS1HPGD | |
| SCHEMBL8180294 | 0.84 | NPSR1 (0.48) | NPSR1MAPTDAOCTPS1HPGD | |
| SCHEMBL1401548 | 0.82 | NPSR1 (0.47) | NPSR1MAPTDAOCTPS1HPGD | |
| SCHEMBL127894 | 0.81 | NPSR1 (0.46) | NPSR1MAPTDAOCTPS1HPGD | |
| SCHEMBL1401554 | 0.81 | NPSR1 (0.46) | NPSR1MAPTDAOCTPS1HPGD | |
| SCHEMBL5879739 | 0.81 | LOXL2 (0.49) | NPSR1MAPTDAOCTPS1HPGD | |
| SCHEMBL4208760 | 0.80 | MAPT (0.42) | NPSR1MAPTDAOCTPS1HPGD | |
| SCHEMBL8226496 | 0.79 | DAO (0.47) | NPSR1MAPTDAOCTPS1HPGD | |
| SCHEMBL9850003 | 0.79 | CYP4A11 (0.49) | NPSR1MAPTDAOCTPS1HPGD | |
| SCHEMBL20996774 | 0.79 | NPSR1 (0.41) | NPSR1MAPTDAOCTPS1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139856-A2 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS, INC. (US) | 2007-12-06 | — | — | WO | disclosed |