⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11303462 | 0.97 | — | — | |
| SCHEMBL9809865 | 0.82 | LMNA (0.33) | — | |
| SCHEMBL3067485 | 0.77 | — | — | |
| Urea SCHEMBL28673164 | 0.76 | — | — | |
| SCHEMBL9421863 | 0.75 | — | — | |
| SCHEMBL7172001 | 0.74 | CRBN (0.41) | — | |
| SCHEMBL10373460 | 0.74 | — | — | |
| SCHEMBL10637178 | 0.74 | — | — | |
| Bicarbonate SCHEMBL11505805 | 0.73 | — | — | |
| SCHEMBL8027843 | 0.72 | CRBN (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327012-A | Naphthalimide guanidino derivative and preparation method and application thereof | 中国农业大学 | 2024-01-02 | — | — | CN | disclosed |
| US-20230255996-A1 | ORAL FORMULATIONS OF CYTIDINE ANALOGS AND METHODS OF USE THEREOF | CELGENE CORPORATION | 2023-08-17 | — | — | US | disclosed |
| CN-113773233-B | Methyl guanidinyl urea derivative and preparation method and application thereof | 中国农业大学 | 2022-05-06 | — | — | CN | disclosed |
| US-7511039-B2 | β-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-7511039-B2 | β-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-20060276408-A1 | Beta-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INCORPORATED (US) | 2006-12-07 | — | — | US | disclosed |
| US-20060276408-A1 | Beta-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INCORPORATED (US) | 2006-12-07 | — | — | US | disclosed |
| EP-0156889-A1 | PHENYLGUANIDINES | SCHERING CORPORATION (US) | 1985-10-09 | — | — | EP | disclosed |
| EP-0147537-A1 | Phenylguanidines | SCHERING CORPORATION (US) | 1985-07-10 | — | — | EP | disclosed |
| WO-1985001283-A1 | PHENYLGUANIDINES | SCHERING CORP. (US) | 1985-03-28 | — | — | WO | disclosed |
| US-4386089-A | BACTERICIDES, GROWTH PROMOTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-31 | — | — | US | disclosed |
| EP-0004956-B1 | BETA-LACTAM ANTIBIOTICS, PROCESS FOR THEIR PREPARATION, FODDER ADDITIVES, DRUGS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0004956-A1 | Beta-lactam antibiotics, process for their preparation, fodder additives, drugs and process for their preparation | BAYER AG (DE) | 1979-10-31 | — | — | EP | disclosed |