Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | MTR | Q99707 | 1/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904939 | 0.83 | HTR2A (0.57) | CTSSCHRM4CHRM1MTRCALCRL | |
| SCHEMBL14098799 | 0.78 | CHRM4 (0.56) | CTSSCHRM4CHRM1CALCRL | |
| SCHEMBL13313600 | 0.77 | BRD4 (0.57) | CTSSCHRM4CHRM1CALCRL | |
| SCHEMBL9046543 | 0.76 | CHRM4 (0.70) | CTSSCHRM4CALCRL | |
| SCHEMBL2872824 | 0.75 | BRD4 (0.56) | CTSSCHRM4CHRM1CALCRL | |
| SCHEMBL27752167 | 0.75 | CHRM4 (0.57) | CHRM4CHRM1CALCRL | |
| SCHEMBL11101376 | 0.73 | CHRM4 (0.52) | CTSSCHRM4CHRM1MTRCALCRL | |
| SCHEMBL12400687 | 0.73 | CHRM4 (0.50) | CTSSCHRM4CHRM1CALCRL | |
| SCHEMBL14410174 | 0.73 | CALCRL (0.54) | CTSSCHRM4CHRM1CALCRL | |
| SCHEMBL13078005 | 0.73 | BRD4 (0.53) | CTSSCHRM4CHRM1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1059922-A2 | GLYCINE TRANSPORT INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-12-20 | — | — | EP | claimed |
| WO-1999044596-A2 | GLYCINE TRANSPORT INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-09-10 | — | — | WO | claimed |