Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19083913 | 0.82 | POLB (0.38) | ALDH1A1POLB | |
| SCHEMBL24425304 | 0.82 | CA2 (0.39) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL6658444 | 0.82 | CA2 (0.39) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL25264601 | 0.80 | CA2 (0.38) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL19083900 | 0.76 | KDM4E (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL21286468 | 0.75 | CA2 (0.43) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL30170310 | 0.74 | CA2 (0.31) | CA2 | |
| SCHEMBL30170322 | 0.74 | CA2 (0.31) | CA2 | |
| SCHEMBL29975028 | 0.72 | CA2 (0.33) | CA2 | |
| SCHEMBL1412322 | 0.71 | CA2 (0.40) | CA2ALDH1A1POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042288-A1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033801-A1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1999-07-08 | — | — | WO | disclosed |