Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12860563 | 0.93 | ADAM17 (0.80) | ADAM17 | |
| SCHEMBL12878377 | 0.87 | ADAM17 (0.82) | ADAM17 | |
| SCHEMBL13218730 | 0.87 | ADAM17 (0.82) | ADAM17 | |
| SCHEMBL8234487 | 0.87 | ADAM17 (0.69) | ADAM17 | |
| SCHEMBL12860703 | 0.86 | ADAM17 (0.83) | ADAM17 | |
| SCHEMBL6009435 | 0.86 | ADAM17 (0.80) | ADAM17 | |
| SCHEMBL10131348 | 0.85 | ADAM17 (0.83) | ADAM17 | |
| SCHEMBL10131390 | 0.85 | ADAM17 (0.83) | ADAM17 | |
| SCHEMBL12860464 | 0.85 | ADAM17 (0.78) | ADAM17 | |
| SCHEMBL12862444 | 0.85 | ADAM17 (0.78) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084451-A1 | HYDANTOIN DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |