Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.55 |
| ▸ | AGER | Q15109 | 3/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220871 | 0.94 | THRB (0.55) | THRBAGERSLC6A9SLC6A5MTNR1A | |
| SCHEMBL8228557 | 0.92 | THRB (0.58) | THRBAGERMTNR1AHDAC1HDAC6 | |
| SCHEMBL8228162 | 0.91 | THRB (0.57) | THRBAGERMTNR1AHDAC1HDAC6 | |
| SCHEMBL8229490 | 0.88 | THRB (0.55) | THRBAGERHDAC1HDAC6 | |
| SCHEMBL8226117 | 0.88 | THRB (0.55) | THRBAGERHDAC1 | |
| SCHEMBL8226057 | 0.86 | THRB (0.52) | THRBAGERMTNR1AHDAC1HDAC6 | |
| SCHEMBL8225187 | 0.86 | THRB (0.59) | THRBSLC6A9SLC6A5HDAC1HDAC6 | |
| SCHEMBL8219823 | 0.86 | THRB (0.63) | THRBHDAC1HDAC6 | |
| SCHEMBL8228011 | 0.85 | THRB (0.59) | THRBAGERHDAC1HDAC6 | |
| SCHEMBL8220856 | 0.85 | THRB (0.62) | THRBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |