Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664936 | 0.82 | TRIM24 (0.50) | TRIM24TRIM33TDP1RAB9AALDH1A1 | |
| SCHEMBL6571919 | 0.82 | ALDH1A1 (0.46) | TRIM24TRIM33TDP1NPC1RAB9A | |
| SCHEMBL31488266 | 0.79 | ERN1 (0.59) | TRIM24TRIM33TDP1NPC1RAB9A | |
| SCHEMBL13350048 | 0.79 | ERN1 (0.59) | TRIM24TRIM33TDP1NPC1RAB9A | |
| SCHEMBL9152842 | 0.79 | TRIM24 (0.47) | TRIM24TRIM33TDP1NPC1RAB9A | |
| SCHEMBL1380630 | 0.79 | ERN1 (0.41) | TRIM24TRIM33TDP1NPC1RAB9A | |
| SCHEMBL6573481 | 0.79 | PDE10A (0.52) | TDP1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12760781 | 0.79 | TRIM24 (0.67) | TRIM24TRIM33TDP1ALDH1A1TSHR | |
| SCHEMBL30880219 | 0.77 | PDE10A (0.64) | TDP1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29518540 | 0.77 | PDE10A (0.64) | TDP1NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007101247-A2 | COMPOSITIONS AND METHODS TO TREAT DISEASES CHARACTERIZED BY CELLULAR PROLIFERATION AND ANGIOGENESIS | PALOMA PHARMACEUTICALS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |