Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370004 | 0.79 | NUDT1 (0.56) | NUDT1ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL10117907 | 0.75 | ADORA2A (0.50) | NUDT1ALDH1A1HPGDHSD17B10XDH | |
| SCHEMBL10368748 | 0.74 | NUDT1 (0.62) | NUDT1ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL2755511 | 0.72 | KDM4E (0.40) | ALDH1A1KDM4EHPGDTDP1CASP1 | |
| SCHEMBL14422887 | 0.72 | NUDT1 (0.51) | NUDT1ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL10369716 | 0.71 | NUDT1 (0.47) | NUDT1ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL1227746 | 0.69 | KDM4E (0.49) | NUDT1ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL18780843 | 0.69 | ADORA2A (0.49) | NUDT1ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL10815783 | 0.69 | MEN1 (0.50) | NUDT1ALDH1A1KDM4ETDP1CKS1B | |
| SCHEMBL14274943 | 0.67 | MEN1 (0.55) | NUDT1ALDH1A1KDM4EHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540407-B2 | Phospholipid drug analogs | UROGEN PHARMA LTD (IL) | 2017-01-10 | — | — | US | disclosed |
| US-20160090395-A1 | PHOSPHOLIPID DRUG ANALOGS | BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT (GB) | 2016-03-31 | — | — | US | disclosed |
| US-9180183-B2 | Phospholipid drug analogs | TELORMEDIX SA (CH) | 2015-11-10 | — | — | US | disclosed |
| US-9173936-B2 | Phospholipid drug analogs | TELORMEDIX SA (CH) | 2015-11-03 | — | — | US | disclosed |
| US-9173935-B2 | Phospholipid drug analogs | TELORMEDIX SA (CH) | 2015-11-03 | — | — | US | disclosed |
| US-9050319-B2 | Phospholipid drug analogs | TELORMEDIX, SA (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20130273144-A1 | PHOSPHOLIPID DRUG ANALOGS | BIOPHARMA CREDIT PLC (GB) | 2013-10-17 | — | — | US | disclosed |
| US-20130267481-A1 | PHOSPHOLIPID DRUG ANALOGS | BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT (GB) | 2013-10-10 | — | — | US | disclosed |
| US-20130266635-A1 | PHOSPHOLIPID DRUG ANALOGS | BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT (GB) | 2013-10-10 | — | — | US | disclosed |
| US-20120009247-A1 | PHOSPHOLIPID DRUG ANALOGS | BIOPHARMA CREDIT PLC (GB) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267481-A1 | PHOSPHOLIPID DRUG ANALOGS | PHOSPHO1, PXMP4, SGMS1 | NUDT1 1425/4885ALDH1A1 3167/4885KDM4E 1139/4885 |
| US-20130273144-A1 | PHOSPHOLIPID DRUG ANALOGS | PHOSPHO1, PXMP4, SGMS1 | NUDT1 1425/4885ALDH1A1 3167/4885KDM4E 1139/4885 |
| US-20160090395-A1 | PHOSPHOLIPID DRUG ANALOGS | PHOSPHO1, PXMP4, SGMS1 | NUDT1 1425/4885ALDH1A1 3167/4885KDM4E 1139/4885 |
| US-20130266635-A1 | PHOSPHOLIPID DRUG ANALOGS | PHOSPHO1, PXMP4, SGMS1 | NUDT1 1425/4885ALDH1A1 3167/4885KDM4E 1139/4885 |
| US-20120009247-A1 | PHOSPHOLIPID DRUG ANALOGS | PHOSPHO1, PXMP4, SGMS1 | NUDT1 1425/4885ALDH1A1 3167/4885KDM4E 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.