Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT1A1 | P22309 | 3/20 | 0.73 |
| ▸ | MLNR | O43193 | 1/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.73 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.73 |
| ▸ | CCKAR | P32238 | 1/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.73 |
| ▸ | GHSR | Q92847 | 1/20 | 0.73 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.73 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822599 | 0.94 | UGT1A1 (0.83) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL8228540 | 0.94 | UGT1A1 (0.83) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL8223501 | 0.94 | UGT1A1 (0.83) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL8200543 | 0.94 | UGT1A1 (0.83) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL1705393 | 0.94 | UGT1A1 (0.83) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL10204009 | 0.94 | UGT1A1 (0.83) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL8231384 | 0.94 | UGT1A1 (0.83) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL14240041 | 0.94 | UGT1A1 (0.83) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL7820596 | 0.92 | UGT1A1 (0.72) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL14479844 | 0.92 | UGT1A1 (0.72) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011117-A2 | ANTIVIRAL PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | disclosed |