Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20074446 | 0.78 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL21278019 | 0.76 | TGFBR1 (0.89) | TGFBR1MAPK14 | |
| SCHEMBL8229195 | 0.75 | TGFBR1 (0.56) | TGFBR1MAPK14 | |
| SCHEMBL21733852 | 0.74 | TGFBR1 (0.63) | TGFBR1MAPK14 | |
| SCHEMBL8235001 | 0.71 | TGFBR1 (0.54) | TGFBR1MAPK14 | |
| SCHEMBL8237874 | 0.71 | TGFBR1 (0.52) | TGFBR1MAPK14 | |
| SCHEMBL410500 | 0.71 | TGFBR1 (0.65) | TGFBR1MAPK14 | |
| SCHEMBL412127 | 0.69 | TGFBR1 (0.62) | TGFBR1MAPK14 | |
| SCHEMBL21447718 | 0.68 | TGFBR1 (0.54) | TGFBR1MAPK14 | |
| SCHEMBL18030742 | 0.68 | TGFBR1 (0.74) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076127-A2 | CONDENSED IMIDAZOLES OR PYRAZOLES AND THEIR USE AS TRANSFORMING GROWTH FACTOR MODULATORS | BIOGEN IDEC MA INC (US) | 2007-07-05 | — | — | WO | disclosed |