Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2326044 | 0.88 | REN (0.57) | RENCYP3A4USP30STSANO1 | |
| SCHEMBL2326055 | 0.88 | REN (0.57) | RENCYP3A4USP30STSANO1 | |
| SCHEMBL2326048 | 0.88 | REN (0.57) | RENCYP3A4USP30STSANO1 | |
| SCHEMBL3607435 | 0.88 | REN (0.49) | RENCYP3A4USP30STSANO1 | |
| SCHEMBL3607433 | 0.88 | REN (0.49) | RENCYP3A4USP30STSANO1 | |
| SCHEMBL3607432 | 0.88 | REN (0.49) | RENCYP3A4USP30STSANO1 | |
| SCHEMBL3605216 | 0.88 | USP30 (0.48) | RENCYP3A4USP30STSANO1 | |
| SCHEMBL968957 | 0.88 | USP30 (0.48) | RENCYP3A4USP30STSANO1 | |
| SCHEMBL968955 | 0.88 | USP30 (0.48) | RENCYP3A4USP30STSANO1 | |
| SCHEMBL970137 | 0.88 | USP30 (0.48) | RENCYP3A4USP30STSANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117560-A2 | PIPERIDINE AND MORPHOLINE RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |