SCHEMBL822929

SCHEMBL822929

O=C(c1ccc(Oc2ccc(S(=O)(=O)c3ccc(Cl)cc3)cc2)cc1)c1ccc(Oc2ccc(S(=O)(=O)c3ccc(Cl)cc3)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.56
MAPK1 P28482 2/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP3A4 P08684 1/20 0.55
POLB P06746 2/20 0.51
APEX1 P27695 1/20 0.51
CTDSP1 Q9GZU7 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MMP1 P03956 2/20 0.49
ELANE P08246 1/20 0.49
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.49
SRD5A2 P31213 2/20 0.48
FABP2 P12104 1/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
SLC22A12 Q96S37 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PRMT1 Q99873 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809347 1.00 HPGD (0.56) HPGDMAPK1ALDH1A1CYP3A4POLB
SCHEMBL12960262 1.00 HPGD (0.56) HPGDMAPK1ALDH1A1CYP3A4POLB
SCHEMBL12960261 1.00 HPGD (0.56) HPGDMAPK1ALDH1A1CYP3A4POLB
SCHEMBL17207952 1.00 HPGD (0.56) HPGDMAPK1ALDH1A1CYP3A4POLB
SCHEMBL17207958 0.95 HPGD (0.51) HPGDMAPK1ALDH1A1CYP3A4POLB
SCHEMBL17209197 0.94 MAPK1 (0.61) HPGDMAPK1ALDH1A1CYP3A4POLB
SCHEMBL17209192 0.90 HPGD (0.50) HPGDMAPK1ALDH1A1CYP3A4POLB
SCHEMBL5527337 0.89 MAPK1 (0.70) HPGDMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL9475034 0.89 MAPK1 (0.70) HPGDMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL7822703 0.88 POLB (0.66) MAPK1ALDH1A1CYP3A4POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
US-8236920-B2 Polyarylene and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 US disclosed
US-8088883-B2 Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-03 US disclosed
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2011-11-10 US disclosed
US-20110275780-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMCIAL COMPANY LIMITED 2011-11-10 US disclosed
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED 2011-02-24 US disclosed
US-7893303-B2 Polyarylene, process for producing the same, solid polyelectrolyte, and proton-conductive film JSR CORPORATION (JP) 2011-02-22 US disclosed
US-20100292481-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2010-11-18 US disclosed
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 US disclosed
US-20090326188-A1 Method for producing polyarylene SUMITOMO CHEMICAL COMPANY, LIMITED 2009-12-31 US disclosed
US-20090040690-A1 Electrochemical capacitor JSR CORPORATION (JP) 2009-02-12 US disclosed
US-20090036632-A1 Polyarylene and Process for Producing the Same SUMITOMO CHEMICAL COMPANY, LIMITED 2009-02-05 US disclosed
US-20080287646-A1 Polyarylene and Method for Producing the Same SUMITOMO CHEMICAL COMPANY, LIMITED 2008-11-20 US disclosed
US-7396607-B2 Manufacturing process for membrane-electrode assemblies JSR CORPORATION (JP) 2008-07-08 US disclosed
US-7348089-B2 Membrane-electrode assembly for direct methanol type fuel cell and proton conductive membrane JSR CORPORATION (JP) 2008-03-25 US disclosed
US-20080015389-A1 Polyarylene, Process For Producing The Same, Solid Polyelectrolyte, And Proton-Conductive Film JSR CORPORATION (JP) 2008-01-17 US disclosed
US-7163988-B2 Aromatic sulfonic acid ester derivative, polyarylene, polyarylene having sulfonic acid group and process for producing the same, and polymer solid electrolyte and proton-conductive membrane JSR CORPORATION (JP) 2007-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND C9, H1-10, CYP1A1 HPGD 3914/4885MAPK1 1740/4885ALDH1A1 46/4885
US-20080015389-A1 Polyarylene, Process For Producing The Same, Solid Polyelectrolyte, And Proton-Conductive Film PARG, PUF60, PARN HPGD 3219/4885MAPK1 1651/4885ALDH1A1 3441/4885
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP1M1 HPGD 3558/4885MAPK1 814/4885ALDH1A1 974/4885
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP2M1 HPGD 3311/4885MAPK1 744/4885ALDH1A1 1092/4885
US-20090036632-A1 Polyarylene and Process for Producing the Same CYP1A1, CYP1B1, C1R HPGD 4179/4885MAPK1 1418/4885ALDH1A1 1881/4885
US-20080287646-A1 Polyarylene and Method for Producing the Same CYP1A1, C1R, CBR1 HPGD 4241/4885MAPK1 2503/4885ALDH1A1 602/4885
US-20100292481-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND TYR, PAH, AHR HPGD 2013/4885MAPK1 2094/4885ALDH1A1 816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.