Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.60 |
| ▸ | HTR2A | P28223 | 15/20 | 0.60 |
| ▸ | HTR1A | P08908 | 8/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.60 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.60 |
| ▸ | HRH1 | P35367 | 3/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.60 |
| ▸ | DRD1 | P21728 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 2/20 | 0.60 |
| ▸ | DRD5 | P21918 | 2/20 | 0.60 |
| ▸ | HTR1D | P28221 | 2/20 | 0.60 |
| ▸ | HTR1B | P28222 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5263913 | 0.91 | DRD2 (0.61) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| Hydrochloric Acid SCHEMBL6919132 | 0.90 | DRD2 (0.60) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL8027267 | 0.88 | DRD2 (0.58) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL5261132 | 0.88 | DRD2 (0.58) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL5261135 | 0.88 | DRD2 (0.58) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL8334007 | 0.85 | HTR2A (0.61) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL7140214 | 0.77 | HTR2A (0.61) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL9490905 | 0.77 | DRD2 (0.72) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL28424510 | 0.76 | HTR2A (0.63) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL7347543 | 0.76 | DRD2 (0.73) | DRD2HTR2AHTR1AKCNH2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093870-A2 | A PROCESS FOR THE PREPARATION OF RISPERIDONE | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2007-08-23 | — | — | WO | disclosed |