Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877508 | 0.78 | HDAC6 (0.48) | EPHX2HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL876367 | 0.78 | HDAC6 (0.48) | EPHX2HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL13340053 | 0.78 | HDAC6 (0.48) | EPHX2HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL8576437 | 0.65 | OPRK1 (0.54) | EPHX2HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL8576433 | 0.65 | OPRK1 (0.54) | EPHX2HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL8111661 | 0.64 | HDAC6 (0.47) | EPHX2TSHRALDH1A1HDAC6HDAC1 | |
| SCHEMBL28142219 | 0.64 | HDAC6 (0.61) | EPHX2KMT2AMEN1HDAC6HDAC1 | |
| SCHEMBL12879107 | 0.64 | HDAC6 (0.61) | EPHX2KMT2AMEN1HDAC6HDAC1 | |
| SCHEMBL28424405 | 0.64 | HDAC6 (0.61) | EPHX2KMT2AMEN1HDAC6HDAC1 | |
| SCHEMBL8110968 | 0.64 | HDAC6 (0.47) | EPHX2ALDH1A1HDAC6HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007094513-A2 | CYCLIC AMINE COMPOUND AND USE THEREOF FOR THE PROPHYLAXIS OR TREATMENT OF HYPERTENSION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | WO | disclosed |