Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13948785 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPTABCC4EPHX2 | |
| SCHEMBL13538038 | 0.98 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTABCC4EPHX2 | |
| SCHEMBL7364154 | 0.94 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTABCC4EPHX2 | |
| SCHEMBL27298904 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTABCC4EPHX2 | |
| SCHEMBL4648318 | 0.80 | EPHX2 (0.49) | ALDH1A1LMNAMAPTEPHX2TSHR | |
| SCHEMBL22117295 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL6372166 | 0.79 | EPHX2 (0.59) | LMNAMAPTEPHX2RECQLUSP2 | |
| SCHEMBL8922213 | 0.79 | EPHX1 (0.53) | ALDH1A1EPHX2TSHRPOLBPOLA1 | |
| SCHEMBL16487142 | 0.79 | EPHX1 (0.53) | ALDH1A1EPHX2TSHRPOLBPOLA1 | |
| SCHEMBL15062648 | 0.79 | EPHX1 (0.53) | ALDH1A1EPHX2TSHRPOLBPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007148135-A1 | MACROCYCLIC COMPOUNDS AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-12-27 | — | — | WO | disclosed |