Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986333 | 0.93 | F10 (0.58) | F10ABCB11F2ST14CYP3A4 | |
| SCHEMBL8230473 | 0.88 | F10 (0.47) | F10 | |
| SCHEMBL3985724 | 0.88 | F10 (0.61) | F10ABCB11F2ST14CYP3A4 | |
| SCHEMBL8230000 | 0.88 | F10 (0.47) | F10F2 | |
| SCHEMBL8232086 | 0.87 | F10 (0.46) | F10 | |
| SCHEMBL3989045 | 0.86 | F10 (0.47) | F10F2 | |
| SCHEMBL3616876 | 0.85 | F10 (0.44) | F10 | |
| SCHEMBL3985616 | 0.84 | F10 (0.61) | F10ABCB11F2ST14CYP3A4 | |
| SCHEMBL8230157 | 0.83 | KDM4E (0.47) | F10KCNH2 | |
| SCHEMBL8230871 | 0.83 | F10 (0.46) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137790-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |