Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232904 | 0.92 | F10 (0.41) | F10F2ABCB1MAPTABCG2 | |
| SCHEMBL3986333 | 0.87 | F10 (0.58) | F10F2 | |
| SCHEMBL8230535 | 0.86 | F10 (0.52) | F10F2 | |
| SCHEMBL3987347 | 0.84 | F10 (0.47) | F10MAPT | |
| SCHEMBL8232688 | 0.81 | F10 (0.47) | F10F2ABCB1MAPTABCG2 | |
| SCHEMBL3985616 | 0.77 | F10 (0.61) | F10F2 | |
| SCHEMBL8224810 | 0.77 | F10 (0.43) | F10F2 | |
| SCHEMBL3382279 | 0.77 | F10 (0.49) | F10 | |
| SCHEMBL8230473 | 0.77 | F10 (0.47) | F10MAPT | |
| SCHEMBL8230002 | 0.76 | F10 (0.41) | F10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029582-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007137790-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |