SCHEMBL8230649

SCHEMBL8230649

CCCCCOC(=O)[C@@H](N)CC(C)C

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.46
SLC7A5 Q01650 1/20 0.45
NOD1 Q9Y239 2/20 0.44
EPHX1 P07099 1/20 0.43
FAAH O00519 1/20 0.42
TSHR P16473 3/20 0.42
HTR2C P28335 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HCAR2 Q8TDS4 2/20 0.41
GRIK1 P39086 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
GRIK2 Q13002 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
RAD52 P43351 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20509278 1.00 NAAA (0.46) NAAASLC7A5NOD1EPHX1FAAH
SCHEMBL7775081 0.98 NAAA (0.48) NAAASLC7A5NOD1EPHX1FAAH
SCHEMBL1479492 0.98 NAAA (0.48) NAAASLC7A5NOD1EPHX1FAAH
SCHEMBL16007698 0.98 NAAA (0.48) NAAASLC7A5NOD1EPHX1FAAH
Hydrochloric Acid SCHEMBL23510791 0.98 NAAA (0.44) NAAASLC7A5NOD1EPHX1FAAH
Hydrochloric Acid SCHEMBL23510792 0.98 NAAA (0.44) NAAASLC7A5NOD1EPHX1FAAH
SCHEMBL10346980 0.98 NAAA (0.48) NAAASLC7A5NOD1EPHX1FAAH
SCHEMBL1479595 0.98 NAAA (0.48) NAAASLC7A5NOD1EPHX1FAAH
SCHEMBL7775084 0.98 NAAA (0.48) NAAASLC7A5NOD1EPHX1FAAH
SCHEMBL1479592 0.98 NAAA (0.48) NAAASLC7A5NOD1EPHX1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110520195-B Novel nucleoside phosphonate prodrugs 勒芬天主教大学 2023-01-17 CN claimed
US-10406086-B2 Moisturizer and cosmetic including the same AJINOMOTO CO., INC. (JP) 2019-09-10 US claimed
CN-109867613-A A kind of Multi substituted benzenes formic acid and its synthetic method 中国科学院大连化学物理研究所 2019-06-11 CN claimed
EP-3366273-A1 MOISTURIZER AND COSMETIC CONTAINING SAME Ajinomoto Co., Inc. (JP) 2018-08-29 EP claimed
US-20180185256-A1 MOISTURIZER AND COSMETIC INCLUDING THE SAME AJINOMOTO CO., INC. (JP) 2018-07-05 US claimed
CN-101347877-A Paste-shaped welding combination XIAMEN JISHIYU FUSE SOLDER CO (CN) 2009-01-21 CN claimed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
CN-110520195-B Novel nucleoside phosphonate prodrugs 勒芬天主教大学 2023-01-17 CN disclosed
US-11040047-B2 Prodrugs of nucleoside phosphonates KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2021-06-22 US disclosed
CN-108837774-B Lacquer wax acyl amino acid surfactant and preparation method thereof 中国林业科学研究院林产化学工业研究所 2020-06-09 CN disclosed
EP-3600556-A1 NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES Katholieke Universiteit Leuven (BE) 2020-02-05 EP disclosed
CN-110520195-A Novel nucleoside phosphonate prodrugs UNIV LEUVEN KATH 2019-11-29 CN disclosed
WO-1996005318-A1 MUTATED PENICILLIN G ACYLASE GENES GIST-BROCADES B.V. (NL) 1996-02-22 WO disclosed
US-5457032-A Having altered substrate specificity GIST-BROCADES NV (NL) 1995-10-10 US disclosed
EP-0453047-B1 Penicillin G acylase, a gene encoding the same and a method for the production of this enzyme GIST BROCADES NV (NL) 1995-07-05 EP disclosed
US-5168048-A Genetic engineering of Alcaligenes GIST-BROCADES NV (NL) 1992-12-01 US disclosed
WO-1991016435-A1 MUTATED BETA-LACTAM ACYLASE GENES GIST-BROCADES N.V. (NL) 1991-10-31 WO disclosed
EP-0453048-A1 Mutated beta-lactam acylase genes GIST-BROCADES N.V. (NL) 1991-10-23 EP disclosed
EP-0453047-A1 Penicillin G acylase, a gene encoding the same and a method for the production of this enzyme GIST-BROCADES N.V. (NL) 1991-10-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11040047-B2 Prodrugs of nucleoside phosphonates PNP, TYMP, PPA1 NAAA 477/4885SLC7A5 1166/4885NOD1 1129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.