Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC3 | Q13489 | 12/20 | 0.36 |
| ▸ | XIAP | P98170 | 9/20 | 0.36 |
| ▸ | TNF | P01375 | 13/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | BIRC7 | Q96CA5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12405729 | 0.84 | BIRC3 (0.39) | BIRC3XIAPTNFBIRC2BIRC7 | |
| SCHEMBL818120 | 0.83 | BIRC3 (0.34) | BIRC3XIAPTNFBIRC2BIRC7 | |
| SCHEMBL820303 | 0.83 | BIRC3 (0.34) | BIRC3XIAPTNFBIRC2BIRC7 | |
| SCHEMBL821708 | 0.81 | DRD2 (0.32) | BIRC3XIAPTNF | |
| SCHEMBL820871 | 0.81 | DRD2 (0.32) | BIRC3XIAPTNF | |
| SCHEMBL15501164 | 0.78 | BIRC3 (0.55) | BIRC3XIAPTNFBIRC2BIRC7 | |
| SCHEMBL12405737 | 0.78 | BIRC3 (0.55) | BIRC3XIAPTNFBIRC2BIRC7 | |
| SCHEMBL820536 | 0.78 | PDE4D (0.31) | BIRC3XIAP | |
| SCHEMBL819547 | 0.77 | BIRC3 (0.47) | BIRC3XIAPTNFBIRC2BIRC7 | |
| SCHEMBL823079 | 0.77 | BIRC3 (0.47) | BIRC3XIAPTNFBIRC2BIRC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288116-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUITCAL CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288116-A1 | IAP INHIBITORS | XIAP, BIRC5, BIRC7 | BIRC3 6/4885XIAP 1/4885TNF 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.