⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019611 | 0.97 | — | — | |
| Benzene SCHEMBL27872529 | 0.95 | ALDH1A1 (0.46) | — | |
| Biphenyl SCHEMBL27458465 | 0.87 | NOTUM (0.44) | — | |
| SCHEMBL3362956 | 0.82 | — | — | |
| SCHEMBL3175909 | 0.80 | MEN1 (0.46) | — | |
| SCHEMBL1104785 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL28018148 | 0.70 | ALDH1A1 (0.48) | — | |
| SCHEMBL9333908 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL31564825 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL3057963 | 0.69 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344287-B | Preparation method of pirfenidone | 山东方明药业集团股份有限公司 | 2025-04-25 | — | — | CN | claimed |
| US-20250129092-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-04-24 | — | — | US | claimed |
| CN-119661429-A | Method for preparing pirfenidone through catalysis of oxalyl dihydrazide polymer copper catalyst | 南京工业大学 | 2025-03-21 | — | — | CN | claimed |
| CN-119118913-A | Preparation method of anti-fibrosis drug pirfenidone | 郑州大学 | 2024-12-13 | — | — | CN | claimed |
| CN-118344287-A | Preparation method of pirfenidone | 山东方明药业集团股份有限公司 | 2024-07-16 | — | — | CN | claimed |
| EP-4396191-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-07-10 | — | — | EP | claimed |
| CN-117776830-A | Full deuteration preparation method of polycyclic aromatic hydrocarbon | 宁波萃英化学技术有限公司 | 2024-03-29 | — | — | CN | claimed |
| WO-2023033740-A9 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2023-12-28 | — | — | WO | claimed |
| CN-117105852-A | Method for efficiently synthesizing pirfenidone | 山东新时代药业有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-110072850-B | 3-sulfonyl-5-aminopyridine-2, 4-diol APJ agonists | 百时美施贵宝公司 | 2023-07-21 | — | — | CN | claimed |
| US-8067162-B2 | Replication; hybridization; kits | RIKEN (JP) | 2011-11-29 | — | — | US | claimed |
| EP-2350090-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2011-08-03 | — | — | EP | claimed |
| US-20110003863-A1 | METHOD FOR SYNTHESIZING PIRFENIDONE | INTERMUNE, INC. (US) | 2011-01-06 | — | — | US | claimed |
| WO-2010141600-A2 | IMPROVED METHOD FOR SYNTHESIZING PIRFENIDONE | INTERMUNE, INC. (US) | 2010-12-09 | — | — | WO | claimed |
| CN-101723883-A | Method for preparing oxycodone | SHANGHAI GENOMICS INC | 2010-06-09 | — | — | CN | claimed |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2010-06-03 | — | — | US | claimed |
| WO-2010045251-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS, INC. (CA) | 2010-04-22 | — | — | WO | claimed |
| CN-101235030-A | 1-substituted-5-trifluoromethyl-2-(1H)pyridone compound, preparation method and use thereof | UNIV CENTRAL SOUTH (CN) | 2008-08-06 | — | — | CN | claimed |
| US-4645839-A | Sulphur dehydrogenation process to yield 5-methyl-2-pyridone | ICI AMERICAS INC. (US) | 1987-02-24 | — | — | US | claimed |
| US-4209467-A | COBALT COMPLEX CATALYST | DAICEL LTD. (JP) | 1980-06-24 | — | — | US | claimed |