Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708891 | 0.95 | — | — | |
| SCHEMBL11933048 | 0.95 | — | — | |
| SCHEMBL143520 | 0.95 | — | — | |
| SCHEMBL3632408 | 0.79 | GABRR1 (0.37) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL14177527 | 0.79 | GABRR1 (0.37) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL15826906 | 0.79 | — | — | |
| Acetic Acid SCHEMBL28430055 | 0.79 | TSHR (0.44) | FFAR3LCKFYNALDH1A1 | |
| SCHEMBL859770 | 0.79 | — | — | |
| SCHEMBL21625547 | 0.79 | SLC1A3 (0.38) | GABRR1CYP1A2 | |
| SCHEMBL8930201 | 0.79 | TSHR (0.44) | GABRR1CYP1A2FOLH1NAALAD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140286-A | Defluxing agent cleaning method and cleaning apparatus | FUJITSU LIMITED (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0811705-B1 | Defluxing agent and cleaning apparatus | FUJITSU LTD (JP) | 2000-08-30 | — | — | EP | disclosed |
| US-6050479-A | Defluxing agent cleaning method and cleaning apparatus | FUJITSU, LTD. (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0627500-B1 | Defluxing agent and cleaning method | FUJITSU LTD (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0811705-A1 | Defluxing agent and cleaning apparatus | FUJITSU LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |
| US-5695571-A | Cleaning method using a defluxing agent | FUJITSU LIMITED (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0627500-A1 | Defluxing agent, cleaning method and cleaning apparatus | FUJITSU LIMITED (JP) | 1994-12-07 | — | — | EP | disclosed |