Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.52 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4260839 | 0.92 | GAA (0.60) | GAAOPRM1OPRD1OPRK1PARP1 | |
| SCHEMBL4578108 | 0.88 | HDAC1 (0.58) | HDAC1TNIKLTA4HCHRM4JAK2 | |
| SCHEMBL4578100 | 0.88 | HDAC1 (0.58) | HDAC1TNIKLTA4HCHRM4JAK2 | |
| SCHEMBL15860138 | 0.88 | HDAC1 (0.58) | HDAC1TNIKLTA4HCHRM4JAK2 | |
| SCHEMBL17313634 | 0.84 | KDM4E (0.58) | HDAC1LTA4HCHRM4KDM4EALDH1A1 | |
| SCHEMBL5179140 | 0.84 | HDAC1 (0.60) | HDAC1GRM2LTA4HCHRM4JAK2 | |
| SCHEMBL17313633 | 0.84 | KDM4E (0.58) | HDAC1LTA4HCHRM4KDM4EALDH1A1 | |
| SCHEMBL8223438 | 0.84 | KDM4E (0.58) | HDAC1LTA4HCHRM4KDM4EALDH1A1 | |
| SCHEMBL4699032 | 0.82 | KDM4E (0.56) | HDAC1LTA4HCHRM4KDM4EALDH1A1 | |
| SCHEMBL28626109 | 0.81 | LTA4H (0.54) | HDAC1GRM2PARP1PARP2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118137-A1 | BENZAMIDE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2007-10-18 | — | — | WO | disclosed |