Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12708695 | 0.77 | — | — | |
| SCHEMBL7530719 | 0.74 | DPP7 (0.46) | DPP4KMT2ADPP8DPP9DPP7 | |
| SCHEMBL10453807 | 0.74 | DPP7 (0.46) | DPP4KMT2ADPP8DPP9DPP7 | |
| SCHEMBL24648735 | 0.67 | DPP7 (0.47) | DPP4KMT2ADPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL8766604 | 0.67 | DPP4 (0.43) | DPP4LAP3 | |
| Hydrochloric Acid SCHEMBL8766608 | 0.67 | DPP4 (0.43) | DPP4LAP3 | |
| SCHEMBL27795879 | 0.66 | CA1 (0.40) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL145524 | 0.66 | — | — | |
| SCHEMBL12340737 | 0.65 | DPP4 (1.00) | DPP4DPP8DPP9DPP7SLC7A5 | |
| SCHEMBL15028064 | 0.65 | DPP4 (1.00) | DPP4DPP8DPP9DPP7SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007100374-A9 | SOFT PROTEASE INHIBITORS AND PRO-SOFT FORMS THEREOF | TUFTS COLLEGE (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007100374-A2 | SOFT PROTEASE INHIBITORS AND PRO-SOFT FORMS THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2007-09-07 | — | — | WO | disclosed |