Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711331 | 0.89 | GSK3B (0.67) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13711329 | 0.89 | GSK3B (0.67) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL8232926 | 0.86 | GSK3B (0.48) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL8234209 | 0.86 | GSK3B (0.48) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL8231807 | 0.81 | GSK3B (0.51) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL8227103 | 0.80 | GSK3B (0.46) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL8235141 | 0.79 | GSK3B (0.44) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13711330 | 0.77 | GSK3B (0.61) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13711336 | 0.77 | GSK3B (0.61) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL13711354 | 0.75 | GSK3B (0.62) | GSK3BCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119463-A1 | 2-(CYCLIC AMINO)-PYRIMIDONE DERIVATIVES AS TPK1 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-10-25 | — | — | WO | disclosed |