Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711438 | 1.00 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL4789585 | 0.87 | GSK3B (0.78) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL698099 | 0.87 | GSK3B (0.78) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8235317 | 0.85 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13711436 | 0.85 | GSK3B (1.00) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL700672 | 0.85 | GSK3B (0.78) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL695353 | 0.85 | GSK3B (0.78) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL696744 | 0.84 | GSK3B (0.73) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8234326 | 0.84 | GSK3B (0.73) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL8235407 | 0.84 | GSK3B (0.79) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569294-B2 | 2-(cyclic amino)-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-10-29 | — | — | US | disclosed |
| US-8569294-B2 | 2-(cyclic amino)-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20090233918-A1 | 2-(CYCLIC AMINO)-PYRIMIDONE DERIVATIVES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20090233918-A1 | 2-(CYCLIC AMINO)-PYRIMIDONE DERIVATIVES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| WO-2007119463-A1 | 2-(CYCLIC AMINO)-PYRIMIDONE DERIVATIVES AS TPK1 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233918-A1 | 2-(CYCLIC AMINO)-PYRIMIDONE DERIVATIVES | MAPT, PRMT1, PSEN1 | GSK3B 140/4885CYP2D6 2510/4885CYP1A2 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.