Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8227001 | 0.90 | GSK3B (0.56) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8234338 | 0.90 | GSK3B (0.57) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8234797 | 0.90 | GSK3B (0.56) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8231884 | 0.90 | GSK3B (0.55) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8235154 | 0.90 | GSK3B (0.55) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL696557 | 0.87 | GSK3B (0.67) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL697606 | 0.86 | GSK3B (0.63) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL4789585 | 0.85 | GSK3B (0.78) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL698099 | 0.85 | GSK3B (0.78) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL703251 | 0.84 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119463-A1 | 2-(CYCLIC AMINO)-PYRIMIDONE DERIVATIVES AS TPK1 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-10-25 | — | — | WO | disclosed |