Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5436570 | 0.96 | IL2 (0.41) | IL2ALDH1A1CYP2C9CYP2C19NPC1 | |
| SCHEMBL5030780 | 0.90 | IL2 (0.45) | IL2ALDH1A1NPC1RAB9ASTIM1 | |
| SCHEMBL5029396 | 0.89 | IL2 (0.48) | IL2ALDH1A1NPC1RAB9ASTIM1 | |
| SCHEMBL5027368 | 0.87 | IL2 (0.43) | IL2ALDH1A1NPC1RAB9ASTIM1 | |
| SCHEMBL8228068 | 0.87 | IL2 (0.45) | IL2ALDH1A1CYP2C9CYP2C19NPC1 | |
| SCHEMBL5029467 | 0.84 | ABCB1 (0.38) | IL2ALDH1A1NPC1RAB9ACREBBP | |
| SCHEMBL5033884 | 0.83 | IL2 (0.49) | IL2ALDH1A1CYP2C9CYP2C19NPC1 | |
| SCHEMBL5032084 | 0.82 | IL2 (0.39) | IL2ALDH1A1CYP2C9CYP2C19NPC1 | |
| SCHEMBL5033765 | 0.82 | IL2 (0.45) | IL2ALDH1A1CYP2C9CYP2C19NPC1 | |
| SCHEMBL8236369 | 0.80 | LMNA (0.39) | ALDH1A1NPC1RAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087429-A2 | PHENYL AND PYRIDYL COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |