Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 3/20 | 0.57 |
| ▸ | ME1 | P48163 | 3/20 | 0.57 |
| ▸ | ME3 | Q16798 | 3/20 | 0.57 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.56 |
| ▸ | CKS1B | P61024 | 1/20 | 0.54 |
| ▸ | SKP1 | P63208 | 1/20 | 0.54 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1904981 | 0.87 | ME2 (0.58) | ME2ME1ME3PANK3CKS1B | |
| SCHEMBL18711280 | 0.84 | PANK3 (0.60) | ME2ME1ME3PANK3CKS1B | |
| SCHEMBL27519720 | 0.83 | AKR1C3 (0.61) | ME2ME1ME3PANK3CKS1B | |
| SCHEMBL3629277 | 0.83 | CKS1B (0.54) | ME2ME1ME3PANK3CKS1B | |
| SCHEMBL16397570 | 0.82 | PANK3 (0.57) | ME2ME1ME3PANK3TRPV1 | |
| SCHEMBL18701794 | 0.80 | PANK3 (0.56) | ME2ME1ME3PANK3CKS1B | |
| SCHEMBL17547308 | 0.80 | SMN1; SMN2 (0.73) | PANK3LMNAMAPTSMN1; SMN2 | |
| SCHEMBL15014105 | 0.80 | PANK3 (0.67) | PANK3CHRM1 | |
| SCHEMBL21522073 | 0.78 | PANK3 (0.54) | ME2ME1ME3PANK3TRPV1 | |
| SCHEMBL21522399 | 0.77 | TIPARP (0.62) | ME2ME1ME3PANK3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |
| WO-2007087135-A2 | PIPERAZINES AND PIPERIDINES AS mGluR5 POTENTIATORS | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |