Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 19/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235267 | 0.87 | ABL1 (0.53) | ABL1 | |
| SCHEMBL10288049 | 0.75 | ABL1 (0.78) | ABL1 | |
| SCHEMBL12283288 | 0.73 | ABL1 (0.53) | ABL1 | |
| SCHEMBL8232417 | 0.73 | PTK2 (0.46) | ABL1 | |
| SCHEMBL12241698 | 0.73 | ABL1 (0.55) | ABL1 | |
| SCHEMBL8235132 | 0.72 | PIK3CD (0.46) | ABL1 | |
| SCHEMBL13170688 | 0.71 | NPC1 (0.54) | ABL1 | |
| SCHEMBL15681775 | 0.70 | ABL1 (0.54) | ABL1 | |
| SCHEMBL14245163 | 0.70 | ABL1 (1.00) | ABL1 | |
| SCHEMBL14297747 | 0.70 | ABL1 (1.00) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087442-A2 | SUBSTITUTED BIARYL COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |