Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 4/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CIT | O14578 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034941 | 0.91 | RAB9A (0.48) | IL2MAPK14NPC1ALDH1A1RAB9A | |
| SCHEMBL5034913 | 0.89 | CIT (0.53) | IL2MAPK14PIK3CDPIK3CGCIT | |
| SCHEMBL8235133 | 0.89 | CIT (0.53) | IL2MAPK14PIK3CDPIK3CGCIT | |
| SCHEMBL5031529 | 0.89 | CIT (0.51) | IL2MAPK14PIK3CDPIK3CGCIT | |
| SCHEMBL5030724 | 0.85 | IL2 (0.50) | IL2MAPK14PIK3CDPIK3CGNPC1 | |
| SCHEMBL5030643 | 0.85 | CIT (0.46) | IL2PIK3CDPIK3CGCITF11 | |
| SCHEMBL8235106 | 0.84 | CIT (0.58) | CIT | |
| SCHEMBL8232850 | 0.83 | CIT (0.56) | IL2MAPK14PIK3CDPIK3CGCIT | |
| SCHEMBL5034886 | 0.82 | CIT (0.44) | IL2MAPK14PIK3CDPIK3CGCIT | |
| SCHEMBL5033022 | 0.82 | IL2 (0.48) | IL2MAPK14PIK3CDPIK3CGNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087442-A2 | SUBSTITUTED BIARYL COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |