Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 4/20 | 0.43 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086151 | 1.00 | GRM2 (0.46) | GRM2CHRM4CAMK2DPARP1FADS1 | |
| SCHEMBL2900422 | 0.94 | CAMK2D (0.44) | CHRM4CAMK2DPARP1FADS1FYN | |
| SCHEMBL8237810 | 0.93 | GRM2 (0.47) | GRM2PARP1FYNPDE1APDE1B | |
| SCHEMBL8234135 | 0.93 | GRM2 (0.47) | GRM2PARP1FYNPDE1APDE1B | |
| SCHEMBL2901567 | 0.93 | GRM2 (0.47) | GRM2PARP1FYNPDE1APDE1B | |
| SCHEMBL13086254 | 0.93 | KDM4E (0.49) | GRM2PARP1FADS1FYNRAD52 | |
| SCHEMBL2943578 | 0.93 | KDM4E (0.49) | GRM2PARP1FADS1FYNRAD52 | |
| SCHEMBL2894075 | 0.93 | KDM4E (0.49) | GRM2PARP1FADS1FYNRAD52 | |
| SCHEMBL8235890 | 0.92 | CHRM4 (0.50) | GRM2CHRM4FADS1KDM4EALDH1A1 | |
| SCHEMBL13086150 | 0.92 | CHRM4 (0.50) | GRM2CHRM4FADS1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007078523-A2 | 5-PHENYL-3-BENZYL-0XAZ0LIDIN-2-0NE DERIVATIVES AND RELATED COMPOUNDS AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | ASTRAZENECA AB (SE) | 2007-07-12 | — | — | WO | disclosed |