Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 9/20 | 0.41 |
| ▸ | CNR2 | P34972 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89739 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRCNR1CNR2L3MBTL1 | |
| SCHEMBL1518539 | 0.84 | ALDH1A1 (0.49) | ALDH1A1TSHRCNR1CNR2L3MBTL1 | |
| SCHEMBL1072555 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TSHRL3MBTL1KDM4EPOLB | |
| SCHEMBL1071788 | 0.80 | CNR1 (0.48) | ALDH1A1TSHRCNR1CNR2L3MBTL1 | |
| SCHEMBL1073010 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRCNR1CNR2L3MBTL1 | |
| SCHEMBL8229613 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TSHRCNR1CNR2L3MBTL1 | |
| SCHEMBL1518688 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRCNR1CNR2L3MBTL1 | |
| SCHEMBL1073181 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRCNR1CNR2L3MBTL1 | |
| SCHEMBL1074356 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRCNR1CNR2L3MBTL1 | |
| SCHEMBL1072102 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRCNR1CNR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077005-A1 | 3 , 5-SUBSTITΓUED PIPERIDINE COMPOUNDS AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2007-07-12 | — | — | WO | disclosed |