Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615223 | 0.91 | KDM4E (0.43) | ALDH1A1KDM4ESMN1; SMN2RCE1TRPV1 | |
| SCHEMBL12603918 | 0.85 | MAPT (0.47) | ALDH1A1KDM4ESMN1; SMN2RCE1TRPV1 | |
| SCHEMBL1780945 | 0.85 | TRPV1 (0.47) | ALDH1A1SMN1; SMN2TRPV1L3MBTL1GAA | |
| SCHEMBL1783971 | 0.84 | TRPV1 (0.45) | ALDH1A1KDM4ESMN1; SMN2RCE1TRPV1 | |
| SCHEMBL8228702 | 0.84 | PDGFRB (0.39) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL989336 | 0.83 | TRPV1 (0.44) | ALDH1A1KDM4ESMN1; SMN2TRPV1L3MBTL1 | |
| SCHEMBL7920420 | 0.83 | TRPV1 (0.44) | ALDH1A1KDM4ESMN1; SMN2RCE1TRPV1 | |
| SCHEMBL8232016 | 0.83 | CYP1A2 (0.36) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL1782050 | 0.83 | TRPV1 (0.44) | ALDH1A1KDM4ESMN1; SMN2RCE1TRPV1 | |
| SCHEMBL1780548 | 0.83 | MAPT (0.39) | ALDH1A1KDM4ESMN1; SMN2TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087443-A2 | VINYL-PHENYL DERIVATIVES FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |