Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989393 | 0.91 | STIM1 (0.42) | MCL1L3MBTL1KDM4EALDH1A1NPC1 | |
| SCHEMBL8228702 | 0.83 | PDGFRB (0.39) | TYK2RAF1BRAFMCL1L3MBTL1 | |
| SCHEMBL989336 | 0.83 | TRPV1 (0.44) | CYP1A2TYK2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8235476 | 0.83 | ALDH1A1 (0.44) | CYP1A2TYK2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1780548 | 0.82 | MAPT (0.39) | TYK2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL8234885 | 0.82 | NPC1 (0.43) | CYP1A2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL987281 | 0.81 | NPC1 (0.43) | TYK2NPC1RAB9AHTTLMNA | |
| SCHEMBL1780945 | 0.80 | TRPV1 (0.47) | TYK2L3MBTL1ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL15654351 | 0.80 | NPC1 (0.43) | TYK2NPC1RAB9AHTTLMNA | |
| SCHEMBL5019605 | 0.79 | L3MBTL1 (0.35) | TYK2MCL1L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087443-A2 | VINYL-PHENYL DERIVATIVES FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |