Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238856 | 0.87 | AR (0.38) | ARHCRTR2HCRTR1 | |
| SCHEMBL8235753 | 0.84 | HRH3 (0.41) | ARCYP3A4 | |
| SCHEMBL5521993 | 0.84 | NCF1 (0.46) | ARCYP3A4 | |
| SCHEMBL8237836 | 0.84 | AR (0.40) | ARHCRTR2HCRTR1 | |
| SCHEMBL5529940 | 0.84 | AR (0.40) | AR | |
| SCHEMBL8231334 | 0.83 | MAPK14 (0.35) | — | |
| SCHEMBL8236219 | 0.83 | HRH3 (0.41) | ARHCRTR2HCRTR1 | |
| SCHEMBL8238871 | 0.80 | NAMPT (0.37) | ARHCRTR2HCRTR1 | |
| SCHEMBL8230091 | 0.80 | SCN8A (0.43) | — | |
| SCHEMBL8238855 | 0.80 | AR (0.38) | ARHCRTR2HCRTR1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |